The ambition of L4MS (Logistics for Manufacturing SMEs) is to reduce the installation cost and time of mobile robots by a factor of 10. It will enable inexpensive deployment of small and flexible logistics solutions requiring no infrastructure change, no production downtime and no in-house expertise. The investment in logistics automation will become extremely attractive for European manufacturing SMEs and Mid-Caps. The use of mobile robots will not only automate the logistics (50% of the production cost) but will also provide unprecedented flexibility on the factory floor for batch production.The L4MS will deliver an open industrial IoT platform called OPIL (Open Platform for Innovations in Logistics) together with a 3D simulator to completely virtualize the intra-factory logistics automation and drastically accelerate the innovation process in this area.In addition, the project will deliver the L4MS marketplace as a one-stop-shop, where European Manufacturing SMEs & Mid-Caps can access the suite of “Smartization services” including technical support, business mentoring, skills and finance. The L4MS technologies and services will conceive 3 Pilots and 20 cross-border Application Experiment to demonstrate highly autonomous, configurable and hybrid (human-robot) logistics solutions driven by the business needs of the manufacturing SMEs and Mid-Caps. This portfolio of 23 cross-border Application Experiments by 50 SMEs selected through 2 competitive Open Calls, will demonstrate the leveraging of European Structural Funds and private investment in established and emerging Digital Innovation Hubs (DIHs) across Europe. The network of DIH and L4MS marketplace will continue to support manufacturing SMEs & Mid-Caps achieve digital excellence and global competitiveness through logistics automation for regions to become entrepreneurial states.